The Substance

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

  • Released:
  • Runtime: 140 minutes
  • Genre: Horror, Drama, Science Fiction
  • Stars: Demi Moore, Margaret Qualley, Gore Abrams, Hugo Diego Garcia, Olivier Raynal, Tiffany Hofstetter, Tom Morton, Axel Baille, Oscar Lesage, Matthew Géczy, Philip Schurer, Namory Bakayoko, Gregory Defleur, Dennis Quaid, Edward Hamilton-Clark, Christian Erickson, Robin Greer, Yann Bean, Vincent Colombe, Jonathon Carley  Show all >
    Jiselle Henderkott, Akil Wingate, Lennard Ridsdale, Jordan Ford Silver, Oscar Salem, Viviane Bossina, Matthew Luret, Jana Bittnerová, Nicolas Royer, Nathan Rippy, Manon Arizmendi, Brett Gillen, Charlotte Marquardt, Aurélien Lorgnier, Ivan Sellier, Christian Bordeleau, Patrick Hamel, Jacques-Yves Dorges, Charlotte Murray, Virginie Kotlinski, Gaëlle Raymond, Claire Lemaire, Didier D'Hondt, Olivier Jarcin, Jean-Luc Magneron, Léa Hengl, Lila Boughoufala, Christian Bourmier, Jean-Claude Matthey, Martin Graham, Jean-Luc Magneron, Billy Bentley, Aaron Kahn, Gabriela Arnon, Nancy Josephson Lahoussine, Andrew Eldridge, Denise Powers, Bryan Jones, Adam Carage, Maria McClurg, Andrew Desmond, Rebecca Lafont, Laura Puech, Ryan Chidester, Céline Vogt, Yannick Guérin, Jean Miel, Paul Descoings, Benoit Lévêque, Arthur Molinet, Manon Sachot, Bastien Jorelle, Kelly Hoarau, Michel Juskiewicz, Louise Greggory, Christophe Sartirano, Florent Torres, Romain Caldeira, Barthelemy Thomas, Ashley Lambert, Ranjani Brow, Chase Fein, Shane Sweet, William Calvert, Michael Corbett, Stephen Apostolina, Kévin Table, Lola Donati, Daria Panchenko, Margot L'Entete, Kate Matthews, Audrey Alcide, Laura Boera, Katrina Budzynski, Annalisa Pagnotta, Aleksandra Fontaine Kedzierska, Eve Marchant, Laureen Cappelliez, Delphine Beaulieu, Clémence Juville, Hillary Sukhonos, Mimi Maury, Cissy Duc, Cara Chapman, Jonathan Jenvrin, Sophie Mercier, Alicia Maury, Pauline Sagetat, Elena Shcheglova, Ophélie Jonard, Katharine Matthews, Amelye Solange, Marie Valton, Megane Adamik, Maelle Dantigny, Agustina Fitzsimons, Pauline Richard, Victoria Brun, Alexandra Faget
  • Director: Coralie Fargeat